Epcoritamab in Previously Treated WM
Description
This is a prospective phase 2, single arm, open label trial to determine if epcoritamab can be used to treat participants with previously treated Waldenstrom Macroglobulinemia (WM). Epcoritamab is a bispecific antibody, a synthetic protein that activates the immune system to target cancer cells.
The U.S. Food and Drug Administration (FDA) has not approved epcoritamab for WM.
The research study procedures include screening for eligibility, in-clinic visits, questionnaires, blood tests, electrocardiograms, bone marrow biopsies, and Computerized Tomography (CT) scans.
Participants will receive study treatment for up to 4 months and will be followed for 24 months.
It is expected that about 20 people will take part in this research study.
Genmab, Inc. is funding this research study by providing the study drug, epcoritamab.
